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New Agents to Treat Life-Threatening Fungal Infections

[ Vol. 8 , Issue. 7 ]

Author(s):

Pauline C. Ting and Scott S. Walker   Pages 592 - 602 ( 11 )

Abstract:


Fungi can cause life threatening diseases, particularly in patients with weakened immune systems. While treatment options are available for these individuals, dose limiting toxicity and the appearance of drug resistant organisms are growing problems. Therefore, the identification, development, and registration of new, safe, and efficacious agents are needed. Herein, we review recent developments in the field of antifungal drug discovery. We focus on recently launched drugs (triazoles and echinocandins), agents in clinical development, and compounds in discovery.

, New, Agents, to, Treat, Life-Threatening, Fungal, Infections

Affiliation:

Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA.



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