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An Overview of Currently Available Antimalarials

[ Vol. 17 , Issue. 19 ]

Author(s):

Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam and Brijesh Rathi*   Pages 2143 - 2157 ( 15 )

Abstract:


Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.

Objective: Overview of currently available antimalarials.

Method: Literary survey.

Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action.

Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.

Keywords:

Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.

Affiliation:

Department of Chemistry of Heterocyclic Compounds, State Scientific Institution “Institute for Single Crystals”, National Academy of Science of Ukraine, Nauky ave. 60, Kharkiv, 61001, Department of Biochemistry and Laboratory Diagnostics, Zaporizhzhia State Medical University, Mayakovsky ave. 26, Zaporizhzhia, 69035, Bio-organic Research Laboratory, Department of Chemistry, Miranda House, Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi-110007

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