Heng Yin, Yuguang Du and Junzeng Zhang Pages 1546 - 1559 ( 14 )
Chitosan is one of the most abundant marine-based biopolymers. Low molecular weight and oligomeric chitosans are water-soluble hydrolysates of chitosan. They have been shown to have a wide range of biological activities and industrial applications. In particular, low molecular weight and oligomeric chitosans have been reported to have the health benefits such as immunity regulation, anti-tumor, liver protection, blood lipids lowering, anti-diabetic, antioxidant and anti-obesity. In this paper, the preparation and analytical methods, and bioactivities of these low molecular weight and oligomeric chitosans were reviewed, with the latest progresses introduced and discussed.
Low molecular weight chitosan (LMWC), chitosan oligosaccharide (COS), preparation, analytical method, bioactivity
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China.