Submit Manuscript  

Article Details


Chemotherapy of Chagas Disease: Status and New Developments

[ Vol. 2 , Issue. 11 ]

Author(s):

Hugo Cerecetto and Mercedes Gonzalez   Pages 1187 - 1213 ( 27 )

Abstract:


Chagas disease is a major parasitic problem in developing countries in Central and South America. Chemotherapy for such disease is still insufficient and not effective in its chronic part. Many efforts have been made in recent years to know more about possible new biochemical targets to design new selective drugs. This paper reviews old therapeutic approaches -Nifurtimox, Benznidazole and related compounds- and the latest rationally developed drugs that prove to be active against different parasitic forms

Keywords:

chemotherapy of chagas disease

Affiliation:

Departamento de Quimica Organica. Facultad de Quimica y Facultad de Ciencias, Universidad de la Republica. Avda. Gral. Flores 2124 CC 1157. 11800 Montevideo Uruguay



Read Full-Text article