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Ghrelin in Hypothalamic Regulation of Energy Balance

[ Vol. 3 , Issue. 8 ]


Tamas L. Horvath, Sabrina Diano and Matthias Tschop   Pages 921 - 927 ( 7 )


The novel peptide hormone ghrelin has recently been recognized as an important co-regulator of growth hormone secretion and energy homeostasis. The significance of ghrelin for obesity and cachexia as well as in the regulation of growth processes is the subject of ongoing basic research as well as clinical studies. It is our goal to emphasize the critical significance of the hypothalamic signaling modalities induced by ghrelin for a better understanding of how this novel hormone affects energy balance and metablism.


metabolism, central regulation, hypothalamus, neurons, peptides, ghrelin


Dept. Ob/Gyn, Yale Medical School, 333 Cedar St. FMB 339, New Haven, CT 06520, USA

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