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COX-2 Inhibitors Celecoxib and Parecoxib: Valuable Options for Postoperative Pain Management

[ Vol. 7 , Issue. 3 ]

Author(s):

Noor M. Gajraj   Pages 235 - 249 ( 15 )

Abstract:


COX-2 inhibitors are equally as efficacious as the non-selective NSAIDs for the treatment of postoperative pain, but have the advantages of a better gastrointestinal side-effect profile as well as a lack of antiplatelet effects. There have been recent concerns regarding the cardiovascular side effects of COX-2 inhibitors. Nonetheless, they remain a valuable option for postoperative pain management. The pharmacology of these agents and available studies are reviewed.

Keywords:

Celecoxib, parecoxib, postoperative pain

Affiliation:

Baylor Center for Pain Management, Baylor University Medical Center, 5575 Warren Parkway Ü, Frisco, Texas 75034.



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