Noor M. Gajraj Pages 235 - 249 ( 15 )
COX-2 inhibitors are equally as efficacious as the non-selective NSAIDs for the treatment of postoperative pain, but have the advantages of a better gastrointestinal side-effect profile as well as a lack of antiplatelet effects. There have been recent concerns regarding the cardiovascular side effects of COX-2 inhibitors. Nonetheless, they remain a valuable option for postoperative pain management. The pharmacology of these agents and available studies are reviewed.
Celecoxib, parecoxib, postoperative pain
Baylor Center for Pain Management, Baylor University Medical Center, 5575 Warren Parkway Ü, Frisco, Texas 75034.