Juan M. Ruso and Natalia Hassan* Pages 1171 - 1187 ( 17 )
Biomacromolecules structures and their interaction between different systems have been extensively studied in the last years. Nevertheless, in the medicinal context, it has not been studied deeply. For this reason, the interest to investigate the behavior of different biomacromolecules such us proteins, organelles, phospholipids, etc. with soft materials has opened new research lines. Computational and experimental methodologies have tried to answer different questions that have been difficult to solve, due to the complexity of the phenomenon, as an example, competition between biomacromolecules and soft materials for a specific organ. In this review, we would like to demonstrate how soft materials influence the biomacromolecules structures and how to change their response, biodistribution and also biocompatibility for future applications.
Biomacromolecules, Immune response, Metabolism, Organelles, Phospholipids, Proteins.
Department of Applied Physics, Soft Matter and Molecular Biophysic Group, University of Santiago de Compostela, Santiago de Compostela 15782, Programa Institucional de Fomento, Universidad Tecnologica Metropolitana. Ignacio Valdivieso 2409, San Joaquin, Santiago