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Recent Advances in the Synthesis of 1,3-Azoles

[ Vol. 16 , Issue. 30 ]

Author(s):

Nadale K. Downer-Riley and Yvette A. Jackson   Pages 3617 - 3626 ( 10 )

Abstract:


The 1,3-azole motif is a common and integral feature of many clinical drugs. Due to their wide-ranging applications, the development of 1,3-azoles as therapeutic agents is an ongoing focus of medicinal chemists. This review highlights the recent approaches towards the assembly of 1,3-oxazole, 1,3-thiazole and 1,3-imidazole motifs.

Keywords:

1, 3-Azoles, Imidazole, Oxazole, Synthesis, Therapeutic agent, Thiazole.

Affiliation:

Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica, West Indies.

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