Nadale K. Downer-Riley and Yvette A. Jackson Pages 3617 - 3626 ( 10 )
The 1,3-azole motif is a common and integral feature of many clinical drugs. Due to their wide-ranging applications, the development of 1,3-azoles as therapeutic agents is an ongoing focus of medicinal chemists. This review highlights the recent approaches towards the assembly of 1,3-oxazole, 1,3-thiazole and 1,3-imidazole motifs.
1, 3-Azoles, Imidazole, Oxazole, Synthesis, Therapeutic agent, Thiazole.
Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica, West Indies.