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Anti-Inflammatory and Pro-Resolving Effects of N-3 PUFA in Cancers: Structures and Mechanisms

[ Vol. 16 , Issue. 8 ]

Author(s):

Qi Wang, Minghua Hu, Huibi Xu and Xiangliang Yang   Pages 888 - 894 ( 7 )

Abstract:


As an important hallmark in cancer progress, inflammation attracts more and more interests in recent years. Lots of evidences support the positive effect of n-3 PUFA in inflammation-associated diseases, the supplement of these fatty acids is thought to be promising in the prevention and treatment of cancers. In this review, we summarize some current knowledge of the mechanisms by which n-3 PUFA are thought to attenuate cancer associated inflammation, and we also introduce the current situation of n-3 PUFA in clinic.

Keywords:

Anti-inflammation, Breast cancer, Colorectal cancer, Microenvironment, n-3 PUFA, Specialized pro-resolving mediators.

Affiliation:

No.1037 Luoyu Road, Wuhan 430074, Hubei, China.

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