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Interest of Antioxidant Agents in Parasitic Diseases. The Case Study of Coumarins

[ Vol. 15 , Issue. 9 ]

Author(s):

Roberto Figueroa-Guiñez, Maria João Matos, Saleta Vazquez-Rodriguez, Lourdes Santana, Eugenio Uriarte, Fernanda Borges, Claudio Olea-Azar and Juan Diego Maya   Pages 850 - 856 ( 7 )

Abstract:


Tropical parasitic diseases, especially those produced by protozoan parasites, are a major public health problem in many countries, and their impact in the health burden is significant. Oxidative processes proved to be related to these diseases, being the antioxidant agents promising therapeutic solutions for them. Therefore, this review provides an overview of published manuscripts regarding both activities. In particular, the interest of the coumarin derivatives as antioxidant agents with application in parasitic diseases is discussed in this manuscript. The recent findings in this field are highlighted.

Keywords:

Antioxidant, Coumarins, Oxidative stress, Parasitic diseases.

Affiliation:

Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago., Departamento de Farmacología Molecular y Clínica, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

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