Submit Manuscript  

Article Details


Spin Trapping: An Essential Tool for the Study of Diseases Caused by Oxidative Stress

[ Vol. 15 , Issue. 5 ]

Author(s):

German Barriga-Gonzalez, Claudio Olea-Azar, Maria C. Zuniga-Lopez, Christian Folch-Cano, Benjamin Aguilera-Venegas, Williams Porcal, Mercedes Gonzalez and Hugo Cerecetto   Pages 484 - 495 ( 12 )

Abstract:


Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping technique, has allowed us to study and understand how free radicals are involved in various pathologies. In this review, the importance of spin trapping technique in the study of diseases such as cancer, diabetes, hypertension and parasitic diseases is discussed. In addition, advances in the use of this technique as therapeutic agents and other interesting applications as the immuno-spin trapping technique are reviewed.

Keywords:

DMPO, EPR, ESR, Human diseases, Immuno-spin trapping, Oxidative stress, PBN, Spin traps.

Affiliation:

Universidad Andres Bello, Facultad de Ciencias Exactas, Departamento de Ciencias Quimicas, Avenida Republica 275, 8370146 Santiago, Chile.

Graphical Abstract:



Read Full-Text article