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New Synthetic Antibiotics for the Treatment of Enterococcus and Campylobacter Infection

[ Vol. 14 , Issue. 1 ]

Author(s):

Hai-Wei Xu, Shang-Shang Qin and Hong-Min Liu   Pages 21 - 39 ( 19 )

Abstract:


Bacterial resistance to antibiotics, particularly to multiple drug resistant antibiotics, is becoming cause for significant concern. The only really viable course of action is to discover new antibiotics with novel mode of actions. This review focuses on antibiotic resistance mechanisms of Enterococcus and Campylobacter, and new antibacterial agents against Enterococcus and Campylobacter through de novo or semi- synthesis in the period from 2003 until mid- 2013.

Keywords:

Antibiotic, Enterococcus, Campylobacter, multiple drug resistant, mechanisms.

Affiliation:

New Drug Research & Development Center, School of Pharmaceutical Sciences, Zhengzhou University, No. 100, KeXue DaDao, Zhengzhou 450001, China.



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