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Recent Advances in the Synthesis of New Antimycobacterial Agents Based on the 1H-1,2,3-Triazoles

[ Vol. 13 , Issue. 22 ]

Author(s):

Daniel Tadeu G. Gonzaga, David R. da Rocha, Fernando de C. da Silva and Vitor F. Ferreira   Pages 2850 - 2865 ( 16 )

Abstract:


The 1H-1,2,3-triazoles have been studied for many years as an important class of heterocyclic compounds and still attracting considerable attention due to their several application such as, organocatalyst, ionic liquid and broad range of biological activities, including several neglected diseases as tuberculosis. This review emphasizes the recent advances of these triazoles and their perspective in the development of new bioactive chemical entities against tuberculosis.

Keywords:

Antimycobacterial agents, inhibitors of glycosidases, 1H-1, 2, 3-triazoles, 1, 4-1H-1, 2, 3-triazoles, 1, 4, 5-1H-1, 2, 3- triazoles, tuberculosis.

Affiliation:

Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, 24020- 150, Niterói, RJ, Brazil.



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